App-V/Softgrid virtual application failed to launch

Hello,
I have the following weird error message when launching an App-V/Softgrid virtual application. The error shows “the application virtualization client could not launch defaultApp”. I have tried it with the default app. How can I get the resolution? I want to remove this error with your proper solution. Help me.
Thanks.

Error: the application virtualization client could not launch defaultApp MFC application 1.0.0.1. No connection could be made because the target machine actively refused it. Error code: 460165019D07D2A-0000274D
