Application Blocked for Security Failed to validate certificate

I know this might be a simple error or issue but this error makes me mad. When I try to access web tools from internet explorer, I stuck up with this error message all the time. I am not a technical person with great knowledge. Please help me sort the error and fix the problem. Is this related with antivirus software in the system? Please help. Thanks.

Application Blocked for Security
Failed to validate certificate.
The application will not be executed.
