Can A Microwave Affect The Nutritional Content Of Food?

Hello, I have been thinking of these few issues for a couple of weeks now and I would be glad if someone can help me by providing answers that would clear all my doubts. I would like to know if the use of the microwave does have a significant quality effect on the nutritional content of food. Are there any studies to prove a loss in nutrition due to the use of the microwave? And apart from what I do seek for, are there any other important information that even most people do not know of yet, causing a lot of havoc? Thank you.
